Sedating chemical chloroform
Some sedatives can cause psychological and physical dependence when taken regularly over a period of time, even at therapeutic doses.
This has led to chloral hydrate being replaced by alternative reagents in microscopy procedures.
By the time the American Civil War broke out in 1861, both ether and chloroform had been in use for several years as methods of surgical anesthesia.
Though both anesthetic agents were developed around the same time (the 1840s), chloroform soon emerged as the more widely used, as it took action faster and was non-flammable.
Sigmund Freud extolled the virtues of cocaine for its supposed ability to treat depression and impotence, while Coca-Cola’s initial popularity may have been due in part to it having the drug among its ingredients.
Many medicinal beverages and tonics began to contain cocaine – long-term users of which may suffer seriously disrupted eating and sleeping patterns, psychotic delusions and hallucinations, not to mention severe depression upon withdrawal.At higher doses it may result in slurred speech, staggering gait, poor judgment, and slow, uncertain reflexes.